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Evidence of vasculature and chondrocyte to osteoblast transdifferentiation in craniofacial synovial joints: implications for osteoarthritis diagnosis and therapy

Temporomandibular joint osteoarthritis (TMJ OA) leads to permanent cartilage destruction, jaw dysfunction, and compromises quality of life. However, the pathological mechanisms governing TMJ OA are poorly understood. Unlike appendicular articular cartilage, the TMJ has two distinct functions as the...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Ruscitto, Angela, Morel, Mallory M, Shawber, Carrie J, Reeve, Gwendolyn, Lecholop, Michael K, Bonthius, Daniel, Yao, Hai, Embree, Mildred C
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380713/
https://ncbi.nlm.nih.gov/pubmed/32030828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902287R
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