Targeting nitric oxide production in microglia with novel imidazodiazepines for non-sedative pain treatment

The goal of this research is the identification of new treatments for neuropathic pain. We characterized the GABAergic system of immortalized mouse and human microglia using electrophysiology and qRT-PCR. Cells from both species exhibited membrane current changes in response to γ-aminobutyric acid,...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Nieman, Amanda N., Li, Guanguan, Zahn, Nicolas M., Mian, Md Yeunus, Mikulsky, Brandon N., Hoffman, Dylan A., Wilcox, Taylor M., Kehoe, Alexander S., Luecke, Ian W., Poe, Michael M., Alvarez-Carbonell, David, Cook, James M., Stafford, Douglas C., Arnold, Leggy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380323/
https://ncbi.nlm.nih.gov/pubmed/32511908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00324
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