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Spontaneous and photosensitization-induced mutations in primary mouse cells transitioning through senescence and immortalization

To investigate the role of oxidative stress–induced DNA damage and mutagenesis in cellular senescence and immortalization, here we profiled spontaneous and methylene blue plus light–induced mutations in the cII gene from λ phage in transgenic mouse embryonic fibroblasts during the transition from pr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Caliri, Andrew W., Tommasi, Stella, Bates, Steven E., Besaratinia, Ahmad
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380187/
https://ncbi.nlm.nih.gov/pubmed/32487750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014465
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