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Spontaneous and photosensitization-induced mutations in primary mouse cells transitioning through senescence and immortalization
To investigate the role of oxidative stress–induced DNA damage and mutagenesis in cellular senescence and immortalization, here we profiled spontaneous and methylene blue plus light–induced mutations in the cII gene from λ phage in transgenic mouse embryonic fibroblasts during the transition from pr...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380187/ https://ncbi.nlm.nih.gov/pubmed/32487750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014465 |
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