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Porcine cytochrome 2A19 and 2E1

Cytochrome P450 (CYP) is a major group of enzymes, which conduct Phase I metabolism. Among commonly used animal models, the pig has been suggested as the most suitable model for investigating drug metabolism in human beings. Moreover, porcine CYP2A19 and CYP2E1 are responsible for the biotransformat...

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書目詳細資料
發表在:Basic Clin Pharmacol Toxicol
Main Authors: Burkina, Viktoriia, Rasmussen, Martin Krøyer, Oliinychenko, Yelyzaveta, Zamaratskaia, Galia
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379952/
https://ncbi.nlm.nih.gov/pubmed/30171805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.13121
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