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Porcine cytochrome 2A19 and 2E1

Cytochrome P450 (CYP) is a major group of enzymes, which conduct Phase I metabolism. Among commonly used animal models, the pig has been suggested as the most suitable model for investigating drug metabolism in human beings. Moreover, porcine CYP2A19 and CYP2E1 are responsible for the biotransformat...

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Detalhes bibliográficos
Publicado no:Basic Clin Pharmacol Toxicol
Main Authors: Burkina, Viktoriia, Rasmussen, Martin Krøyer, Oliinychenko, Yelyzaveta, Zamaratskaia, Galia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379952/
https://ncbi.nlm.nih.gov/pubmed/30171805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.13121
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