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TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF‐κB signaling

This study aimed to investigate the effects of triggering receptor expressed on myeloid cell‐2 (TREM2) on the production of pro‐inflammatory mediators and cytokines induced by lipopolysaccharide (LPS) in BV2 microglia. TREM2 expression or TREM2‐specific siRNA were used to induce TREM2 overexpression...

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Dettagli Bibliografici
Pubblicato in:Cell Biol Int
Autori principali: Li, Caixia, Zhao, Bing, Lin, Caizhao, Gong, Zhiping, An, Xiaoxia
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379930/
https://ncbi.nlm.nih.gov/pubmed/29663649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.10975
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