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TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF‐κB signaling

This study aimed to investigate the effects of triggering receptor expressed on myeloid cell‐2 (TREM2) on the production of pro‐inflammatory mediators and cytokines induced by lipopolysaccharide (LPS) in BV2 microglia. TREM2 expression or TREM2‐specific siRNA were used to induce TREM2 overexpression...

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發表在:Cell Biol Int
Main Authors: Li, Caixia, Zhao, Bing, Lin, Caizhao, Gong, Zhiping, An, Xiaoxia
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379930/
https://ncbi.nlm.nih.gov/pubmed/29663649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.10975
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