TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF‐κB signaling

This study aimed to investigate the effects of triggering receptor expressed on myeloid cell‐2 (TREM2) on the production of pro‐inflammatory mediators and cytokines induced by lipopolysaccharide (LPS) in BV2 microglia. TREM2 expression or TREM2‐specific siRNA were used to induce TREM2 overexpression...

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Vydáno v:Cell Biol Int
Hlavní autoři: Li, Caixia, Zhao, Bing, Lin, Caizhao, Gong, Zhiping, An, Xiaoxia
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379930/
https://ncbi.nlm.nih.gov/pubmed/29663649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.10975
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