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Complete Phase Diagram for Liquid−Liquid Phase Separation of Intrinsically Disordered Proteins

A number of intrinsically disordered proteins have been shown to self-assemble via liquid−liquid phase separation into protein-rich and dilute phases. The resulting coacervates can have important biological functions, and the ability to form these assemblies is dictated by the protein’s primary amin...

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Detalhes bibliográficos
Publicado no:J Phys Chem Lett
Main Authors: McCarty, James, Delaney, Kris T., Danielsen, Scott P. O., Fredrickson, Glenn H., Shea, Joan-Emma
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379843/
https://ncbi.nlm.nih.gov/pubmed/30873835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.9b00099
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