Extending rnaSPAdes functionality for hybrid transcriptome assembly

BACKGROUND: De novo RNA-Seq assembly is a powerful method for analysing transcriptomes when the reference genome is not available or poorly annotated. However, due to the short length of Illumina reads it is usually impossible to reconstruct complete sequences of complex genes and alternative isofor...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Prjibelski, Andrey D., Puglia, Giuseppe D., Antipov, Dmitry, Bushmanova, Elena, Giordano, Daniela, Mikheenko, Alla, Vitale, Domenico, Lapidus, Alla
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Software
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379828/
https://ncbi.nlm.nih.gov/pubmed/32703149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03614-2
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