Extending rnaSPAdes functionality for hybrid transcriptome assembly

BACKGROUND: De novo RNA-Seq assembly is a powerful method for analysing transcriptomes when the reference genome is not available or poorly annotated. However, due to the short length of Illumina reads it is usually impossible to reconstruct complete sequences of complex genes and alternative isofor...

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Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Prjibelski, Andrey D., Puglia, Giuseppe D., Antipov, Dmitry, Bushmanova, Elena, Giordano, Daniela, Mikheenko, Alla, Vitale, Domenico, Lapidus, Alla
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379828/
https://ncbi.nlm.nih.gov/pubmed/32703149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03614-2
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