LncRNA HOTAIR induces sunitinib resistance in renal cancer by acting as a competing endogenous RNA to regulate autophagy of renal cells

BACKGROUND: Cell autophagy has been proposed to be involved in drug resistance therapy. However, how the long non-coding RNA (lncRNA) reduces risks of drug resistance in renal cancer (RC) cells needs a thorough inquiry. This study was assigned to probe the effect and mechanism of HOTAIR on sunitinib...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Li, Dechao, Li, Changfu, Chen, Yongsheng, Teng, Lichen, Cao, Yan, Wang, Wentao, Pan, Hongxin, Xu, Yongpeng, Yang, Dan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379791/
https://ncbi.nlm.nih.gov/pubmed/32760216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01419-0
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