Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion

BACKGROUND: Transfusion is associated with organ failure and nosocomial infection in trauma patients, which may be mediated by soluble bioactive substances in blood products, including extracellular vesicles (EVs). We hypothesize that removing EVs, by washing or filtering of blood products, reduces...

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Veröffentlicht in:Transfusion
Hauptverfasser: Wirtz, Mathijs R., Jurgens, Jordy, Zuurbier, Coert J., Roelofs, Joris J.T.H., Spinella, Philip C., Muszynski, Jennifer A., Carel Goslings, J., Juffermans, Nicole P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2018
Schlagworte:
Transfusion Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379301/
https://ncbi.nlm.nih.gov/pubmed/30461025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15039
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