Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion

BACKGROUND: Transfusion is associated with organ failure and nosocomial infection in trauma patients, which may be mediated by soluble bioactive substances in blood products, including extracellular vesicles (EVs). We hypothesize that removing EVs, by washing or filtering of blood products, reduces...

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Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: Wirtz, Mathijs R., Jurgens, Jordy, Zuurbier, Coert J., Roelofs, Joris J.T.H., Spinella, Philip C., Muszynski, Jennifer A., Carel Goslings, J., Juffermans, Nicole P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Transfusion Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379301/
https://ncbi.nlm.nih.gov/pubmed/30461025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15039
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