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Anti-Retroviral Antibody FcγR-mediated Effector Functions

The antiviral activity of antibodies reflects the bifunctional properties of these molecules. While the Fab domains mediate highly specific antigenic recognition to block virus entry, the Fc domain interacts with diverse types of Fcγ receptors (FcγRs) expressed on the surface of effector leukocytes...

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Foilsithe in:Immunol Rev
Main Authors: Bournazos, Stylianos, Ravetch, Jeffrey V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379163/
https://ncbi.nlm.nih.gov/pubmed/28133801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12482
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