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Evolution of RAS Mutational Status in Liquid Biopsies During First-Line Chemotherapy for Metastatic Colorectal Cancer

Treatment options for patients with metastatic colorectal cancer (mCRC) are limited. This particularly affects the largest group of patients with RAS mutations, who are considered ineligible for therapy with antiEGFR antibodies. In this liquid biopsy-based study, we performed the first in-depth anal...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Klein-Scory, Susanne, Wahner, Ingo, Maslova, Marina, Al-Sewaidi, Yosef, Pohl, Michael, Mika, Thomas, Ladigan, Swetlana, Schroers, Roland, Baraniskin, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378792/
https://ncbi.nlm.nih.gov/pubmed/32766143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01115
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