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Use of Allopurinol to Mitigate 6-Mercaptopurine Associated Gastrointestinal Toxicity in Acute Lymphoblastic Leukemia

An essential component of acute lymphoblastic leukemia (ALL) therapy is the prolonged maintenance phase with daily 6-mercaptopurine (6-MP) as the cornerstone. While 6-MP is generally well-tolerated, some patients suffer from significant side effects such as gastrointestinal (GI) toxicity, including...

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Vydáno v:Front Oncol
Hlavní autoři: Conneely, Shannon E., Cooper, Stacy L., Rau, Rachel E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378397/
https://ncbi.nlm.nih.gov/pubmed/32766146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01129
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