AAV-Mediated Combination Gene Therapy for Neuropathic Pain: GAD65, GDNF, and IL-10

Neuropathic pain is a chronic pain state characterized by nerve damage, inflammation, and nociceptive neuron hyperactivity. As the underlying pathophysiology is complex, a more effective therapy for neuropathic pain would be one that targets multiple elements. Here, we generated recombinant adeno-as...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Kim, Daewook, Kim, Kyung-Ran, Kwon, Yejin, Kim, Minjung, Kim, Min-Ju, Sim, Yeomoon, Ji, Hyelin, Park, Jang-Joon, Cho, Jong-Ho, Choi, Heonsik, Kim, Sujeong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378317/
https://ncbi.nlm.nih.gov/pubmed/32728596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.06.018
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