Photoactivatable oncolytic adenovirus for optogenetic cancer therapy

Virotherapy using oncolytic adenovirus is an effective anticancer strategy. However, the tumor selectivity of oncolytic adenoviruses is not enough high. To develop oncolytic adenovirus with a low risk of off-tumor toxicity, we constructed a photoactivatable oncolytic adenovirus (paOAd). In response...

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Publicado en:Cell Death Dis
Main Authors: Hagihara, Yasuko, Sakamoto, Ayaka, Tokuda, Takashi, Yamashita, Tomoki, Ikemoto, Sena, Kimura, Ayaka, Haruta, Makito, Sasagawa, Kiyotaka, Ohta, Jun, Takayama, Kazuo, Mizuguchi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378209/
https://ncbi.nlm.nih.gov/pubmed/32703933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02782-6
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