Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice

Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with limited therapeutic options. The lack of mouse models that recapitulate the genetics of ACC has hampered progress in the field. We analyzed The Cancer Genome Atlas (TCGA) dataset for ACC and found that patients harboring alterat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Borges, Kleiton Silva, Pignatti, Emanuele, Leng, Sining, Kariyawasam, Dulanjalee, Ruiz-Babot, Gerard, Ramalho, Fernando Silva, Taketo, Makoto Mark, Carlone, Diana L., Breault, David T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Brief Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378041/
https://ncbi.nlm.nih.gov/pubmed/32561853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1358-5
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia