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Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with limited therapeutic options. The lack of mouse models that recapitulate the genetics of ACC has hampered progress in the field. We analyzed The Cancer Genome Atlas (TCGA) dataset for ACC and found that patients harboring alterat...
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Veröffentlicht in: | Oncogene |
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Hauptverfasser: | , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Nature Publishing Group UK
2020
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7378041/ https://ncbi.nlm.nih.gov/pubmed/32561853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1358-5 |
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