Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice

Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with limited therapeutic options. The lack of mouse models that recapitulate the genetics of ACC has hampered progress in the field. We analyzed The Cancer Genome Atlas (TCGA) dataset for ACC and found that patients harboring alterat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogene
Prif Awduron: Borges, Kleiton Silva, Pignatti, Emanuele, Leng, Sining, Kariyawasam, Dulanjalee, Ruiz-Babot, Gerard, Ramalho, Fernando Silva, Taketo, Makoto Mark, Carlone, Diana L., Breault, David T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Brief Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378041/
https://ncbi.nlm.nih.gov/pubmed/32561853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1358-5
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