Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing

Ageing compromises skeletal muscle mass and function through poorly defined molecular aetiology. Here we have used untargeted metabolomics using UHPLC-MS to profile muscle tissue from young (n=10, 25±4y), middle aged (n=18, 50±4y) and older (n=18, 70±3y) men and women (50:50). Random Forest was used...

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Spremljeno u:
Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Wilkinson, Daniel J., Rodriguez-Blanco, Giovanny, Dunn, Warwick B., Phillips, Bethan E., Williams, John P., Greenhaff, Paul L., Smith, Kenneth, Gallagher, Iain J., Atherton, Philip J.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2020
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377844/
https://ncbi.nlm.nih.gov/pubmed/32580166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103513
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