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Monocytes from infliximab-resistant patients with Crohn’s disease exhibit a disordered cytokine profile
Crohn's disease (CD) is a chronic inflammatory disorder characterized by immune response dysregulation. Tumor necrosis factor-α (TNFα) is a key cytokine in the pathogenesis of CD, as indicated by the efficacy of anti-TNF-α therapy with infliximab (IFX). However, approximately 30–40% of CD patie...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376177/ https://ncbi.nlm.nih.gov/pubmed/32699266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68993-1 |
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