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Mutational spectrum and prognosis in NRAS-mutated acute myeloid leukemia
The mutational spectrum and prognostic factors of NRAS-mutated (NRAS(mut)) acute myeloid leukemia (AML) are largely unknown. We performed next-generation sequencing (NGS) in 1,149 cases of de novo AML and discovered 152 NRAS(mut) AML (13%). Of the 152 NRAS(mut) AML, 89% had at least one companion mu...
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| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376066/ https://ncbi.nlm.nih.gov/pubmed/32699322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69194-6 |
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