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A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution
Aneuploidy is a feature of many cancers. Recent studies demonstrate that in the hematopoietic stem and progenitor cell (HSPC) compartment aneuploid cells have reduced fitness and are efficiently purged from the bone marrow. However, early phases of hematopoietic reconstitution following bone marrow...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376010/ https://ncbi.nlm.nih.gov/pubmed/32699207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68729-1 |
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