Antitumor Activity of Combination Therapy with Metformin and Trametinib in Non-Small Cell Lung Cancer Cells

Metformin has been widely used as an antidiabetic drug, and reported to inhibit cell proliferation in many cancers including non-small cell lung cancer (NSCLC). In NSCLC cells, metformin suppresses PI3K/AKT/mTOR signaling pathway, but effect of metformin on RAS/ RAF/MEK/ERK signaling pathway is cont...

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Dades bibliogràfiques
Publicat a:Dev Reprod
Autors principals: Ko, Eunjeong, Baek, Seungjae, Kim, Jiwon, Park, Deokbae, Lee, Youngki
Format: Artigo
Idioma:Inglês
Publicat: Korean Society of Developmental Biology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375979/
https://ncbi.nlm.nih.gov/pubmed/32734128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12717/DR.2020.24.2.113
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