Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells

Celecoxib has potential as an effective antineoplastic agent, but it may exhibit side effects. Given the glucose-addicted properties of tumor cells, metformin is recognized for its inhibitory effect on oxidative phosphorylation. In the present study, we aimed to combine low dose of celecoxib with me...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Cao, Nini, Lu, Yanyan, Liu, Jia, Cai, Fangfang, Xu, Huangru, Chen, Jia, Zhang, Xiangyu, Hua, Zi-Chun, Zhuang, Hongqin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387512/
https://ncbi.nlm.nih.gov/pubmed/32792943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01094
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