Arp2/3 and Mena/VASP Require Profilin 1 for Actin Network Assembly at the Leading Edge

Cells have many types of actin structures, which must assemble from a common monomer pool. Yet, it remains poorly understood how monomers are distributed to and shared between different filament networks. Simplified model systems suggest that monomers are limited and heterogeneous, which alters acti...

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Veröffentlicht in:Curr Biol
Hauptverfasser: Skruber, Kristen, Warp, Peyton V., Shklyarov, Rachael, Thomas, James D., Swanson, Maurice S., Henty-Ridilla, Jessica L., Read, Tracy-Ann, Vitriol, Eric A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375932/
https://ncbi.nlm.nih.gov/pubmed/32470361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.04.085
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