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Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants
Eight separate mutations in the actin-binding protein profilin-1 have been identified as a rare cause of amyotrophic lateral sclerosis (ALS). Profilin is essential for many neuronal cell processes through its regulation of lipids, nuclear signals, and cytoskeletal dynamics, including actin filament...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2022-04-01
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| シリーズ: | European Journal of Cell Biology |
| 主題: | |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S0171933522000152 |
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