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A novel interplay between GEFs orchestrates Cdc42 activity during cell polarity and cytokinesis in fission yeast
Cdc42, a conserved regulator of cell polarity, is activated by two GEFs, Gef1 and Scd1, in fission yeast. Why the cell needs two GEFs is unclear, given that they are partially redundant and activate the same GTPase. Using the GEF localization pattern during cytokinesis as a paradigm, we report a nov...
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| 發表在: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Company of Biologists Ltd
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7375822/ https://ncbi.nlm.nih.gov/pubmed/31719163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.236018 |
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