Group A Streptococcus AdcR Regulon Participates in Bacterial Defense against Host-Mediated Zinc Sequestration and Contributes to Virulence

Colonization by pathogenic bacteria depends on their ability to overcome host nutritional defenses and acquire nutrients. The human pathogen group A streptococcus (GAS) encounters the host defense factor calprotectin (CP) during infection. CP inhibits GAS growth in vitro by imposing zinc (Zn) limita...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Makthal, Nishanth, Do, Hackwon, Wendel, Brian M., Olsen, Randall J., Helmann, John D., Musser, James M., Kumaraswami, Muthiah
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375770/
https://ncbi.nlm.nih.gov/pubmed/32393509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00097-20
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