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The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology

Kabuki syndrome (KS) is a congenital craniofacial disorder resulting from mutations in the KMT2D histone methylase (KS1) or the UTX histone demethylase (KS2). With small cohorts of KS2 patients, it is not clear whether differences exist in clinical manifestations relative to KS1. We mutated KMT2D in...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Shpargel, Karl B., Mangini, Cassidy L., Xie, Guojia, Ge, Kai, Magnuson, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375479/
https://ncbi.nlm.nih.gov/pubmed/32541010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.187997
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