Therapeutic Efficacy and Resistance Selection of a Lipopeptide Fusion Inhibitor in Simian Immunodeficiency Virus-Infected Rhesus Macaques

We recently reported a group of lipopeptide-based membrane fusion inhibitors with potent antiviral activities against human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus (SIV). In this study, the in vivo therapeutic efficacy of such a lipopeptide, LP-52, was evaluat...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Yu, Danwei, Xue, Jing, Wei, Huamian, Cong, Zhe, Chen, Ting, Zhu, Yuanmei, Chong, Huihui, Wei, Qiang, Qin, Chuan, He, Yuxian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375369/
https://ncbi.nlm.nih.gov/pubmed/32404526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00384-20
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