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Alzheimer's amyloid‐β and tau protein accumulation is associated with decreased expression of the LDL receptor‐associated protein in human brain tissue

INTRODUCTION: One of the major neuropathological features of Alzheimer's disease (AD) is the accumulation of amyloid‐β (Aβ) protein in the brain. Evidence suggests that the low‐density lipoprotein receptor‐associated protein (RAP) binds strongly to Aβ and enhances its cellular uptake and that d...

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Dades bibliogràfiques
Publicat a:Brain Behav
Autors principals: Shepherd, Claire E., Affleck, Andrew J., Bahar, Anita Y., Carew‐Jones, Francine, Gregory, Gillian, Small, David H., Halliday, Glenda M.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375106/
https://ncbi.nlm.nih.gov/pubmed/32484608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1672
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