Alzheimer's amyloid‐β and tau protein accumulation is associated with decreased expression of the LDL receptor‐associated protein in human brain tissue

INTRODUCTION: One of the major neuropathological features of Alzheimer's disease (AD) is the accumulation of amyloid‐β (Aβ) protein in the brain. Evidence suggests that the low‐density lipoprotein receptor‐associated protein (RAP) binds strongly to Aβ and enhances its cellular uptake and that d...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Brain Behav
Asıl Yazarlar: Shepherd, Claire E., Affleck, Andrew J., Bahar, Anita Y., Carew‐Jones, Francine, Gregory, Gillian, Small, David H., Halliday, Glenda M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375106/
https://ncbi.nlm.nih.gov/pubmed/32484608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1672
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