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Influence of Calcineurin Inhibitor and Sex on Mycophenolic Acid Pharmacokinetics and Adverse Effects Post-renal Transplant

Tacrolimus or cyclosporine is prescribed with mycophenolic acid posttransplant and contributes to interpatient variability in mycophenolic acid pharmacokinetics and response. Cyclosporine inhibits enterohepatic circulation of the metabolite mycophenolic acid glucuronide, which is not described with...

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Publicat a:J Clin Pharmacol
Autors principals: Meaney, Calvin J., Sudchada, Patcharaporn, Consiglio, Joseph D., Wilding, Gregory E., Cooper, Louise M., Venuto, Rocco C., Tornatore, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375007/
https://ncbi.nlm.nih.gov/pubmed/31062373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1428
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