Selegiline acts as neuroprotective agent against methamphetamine-prompted mood and cognitive related behavior and neurotoxicity in rats: Involvement of CREB/BDNF and Akt/GSK3 signal pathways

OBJECTIVE(S): Present study investigated the neuroprotective effects of selegiline and the molecular mechanisms involved in methamphetamine-induced neurotoxicity. MATERIALS AND METHODS: Male wistar rats were randomly divided into six groups (10 rats in each group). Group 1 and group 2 received norma...

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Publicat a:Iran J Basic Med Sci
Autors principals: Feizipour, Saba, Sobhani, Sarvenaz, Mehrafza, Shafagh, Gholami, Mina, Motaghinejad, Majid, Motevalian, Manijeh, Safari, Sepideh, Davoudizadeh, Reza
Format: Artigo
Idioma:Inglês
Publicat: Mashhad University of Medical Sciences 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374985/
https://ncbi.nlm.nih.gov/pubmed/32742598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.38827.9221
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