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Duloxetine by Modulating the Akt/GSK3 Signaling Pathways Has Neuroprotective Effects against Methamphetamine-Induced Neurodegeneration and Cognition Impairment in Rats

BACKGROUND: The neuroprotective effects of duloxetine, as an antidepressant agent, and the neurodegenerative effects of methamphetamine have been shown in previous studies. Nonetheless, their exact neurochemical and behavioral effects are still unclear. In the current study, we sought to clarify the...

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Publicat a:Iran J Med Sci
Autors principals: Rahimi Borumand, Mehrasa, Motaghinejad, Majid, Motevalian, Manijeh, Gholami, Mina
Format: Artigo
Idioma:Inglês
Publicat: Iranian Journal of Medical Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423432/
https://ncbi.nlm.nih.gov/pubmed/30936601
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