Overexpression of TGFβ1 in murine mesenchymal stem cells improves lung inflammation by impacting the Th17/Treg balance in LPS-induced ARDS mice

BACKGROUND: T helper 17 cells (Th17)/regulatory T cells (Treg), as subtypes of CD4(+) T cells, play an important role in the inflammatory response of acute respiratory distress syndrome (ARDS). However, there is still a lack of effective methods to regulate the differentiation balance of Th17/Treg....

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Gepubliceerd in:Stem Cell Res Ther
Hoofdauteurs: Chen, Jianxiao, Zhang, Xiwen, Xie, Jianfeng, Xue, Ming, Liu, Ling, Yang, Yi, Qiu, Haibo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374869/
https://ncbi.nlm.nih.gov/pubmed/32698911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01826-0
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