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Artesunate influences Th17/Treg lymphocyte balance by modulating Treg apoptosis and Th17 proliferation in a murine model of rheumatoid arthritis

CD4(+) regulatory T (Treg) cells and T-helper 17 (Th17) cells have been shown to have important roles in rheumatoid arthritis (RA). In our previous study, it was demonstrated that artesunate was able to alter the Treg/Th17 ratio in patients with RA; however, the underlying mechanisms remain unclear....

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Bibliografske podrobnosti
izdano v:Exp Ther Med
Main Authors: Liu, Jia, Hong, Xuezhi, Lin, Dong, Luo, Xiaohong, Zhu, Mengya, Mo, Hanyou
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443220/
https://ncbi.nlm.nih.gov/pubmed/28565837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4232
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