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Insulin signaling and glucose metabolism in different hepatoma cell lines deviate from hepatocyte physiology toward a convergent aberrant phenotype

Hepatoma cell lines are widely used to model the hepatocyte for insulin signaling and fatty liver disease. However, a direct comparison of insulin action in primary hepatocytes and in hepatoma cell lines is needed to validate this model and to better understand liver cancer. Here we have investigate...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Molinaro, Angela, Becattini, Barbara, Solinas, Giovanni
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374613/
https://ncbi.nlm.nih.gov/pubmed/32694512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68721-9
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