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Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations

Numerous studies of knockout mice find impacts on microbiota composition that influence host phenotype. However, such differences can vanish when KO mice are compared directly to WT littermates, suggesting these differences do not reflect the genetic deletion per se but microbiota composition drifti...

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Bibliografiske detaljer
Udgivet i:NPJ Biofilms Microbiomes
Main Authors: Viennois, Emilie, Pujada, Adani, Sung, Junsik, Yang, Chunhua, Gewirtz, Andrew T., Chassaing, Benoit, Merlin, Didier
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374158/
https://ncbi.nlm.nih.gov/pubmed/32694535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41522-020-0137-y
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