Critical Role of PepT1 in Promoting Colitis-Associated Cancer and Therapeutic Benefits of the Anti-inflammatory PepT1-Mediated Tripeptide KPV in a Murine Model

BACKGROUND & AIMS: The human intestinal peptide transporter 1 (hPepT1), is expressed in the small intestine at low levels in the healthy colon and up-regulated during inflammatory bowel disease. hPepT1 plays a role in mouse colitis and human studies have shown that chronic intestinal inflammatio...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Viennois, Emilie, Ingersoll, Sarah A., Ayyadurai, Saravanan, Zhao, Yuan, Wang, Lixin, Zhang, Mingzhen, Han, Moon K., Garg, Pallavi, Xiao, Bo, Merlin, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957955/
https://ncbi.nlm.nih.gov/pubmed/27458604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.01.006
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