Dose‐dependent naloxone‐induced morphine withdrawal symptoms in opioid‐dependent males—a double‐blinded, randomized study

AIMS: Oral opioid preparations combined with naloxone are intended to induce a transient acute withdrawal syndrome to avoid intravenous misuse. This trial aimed to establish an appropriate morphine–naloxone dose ratio for an abuse‐deterrent oral opioid formulation. METHODS: In a randomized, double‐b...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Weisshaar, Stefan, Brandt, Laura, Litschauer, Brigitte, Sheik‐Rezaei, Safoura, Moser, Laura, Nirnberger, Günther, Kühberger, Elisabeth, Bauer, Ulrike, Firbas, Christa, Gouya, Ghazaleh, Wolzt, Michael, Fischer, Gabriele
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373709/
https://ncbi.nlm.nih.gov/pubmed/32145041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14271
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