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Discrete Cues Paired with Naloxone-Precipitated Withdrawal from Acute Morphine Dependence Elicit Conditioned Withdrawal Responses

Acute bolus doses of morphine induce a state of acute opioid dependence as measured by naloxone-precipitated withdrawal. Repeated morphine and precipitated withdrawal experience further enhances naloxone-induced withdrawal severity, in part due to direct neuroadaptation to repeated morphine, and in...

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Main Authors: Amitai, Nurith, Liu, Jian, Schulteis, Gery
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266687/
https://ncbi.nlm.nih.gov/pubmed/16571999
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