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Modelling of neutrophil dynamics in children receiving busulfan or treosulfan for haematopoietic stem cell transplant conditioning

AIMS: Busulfan and treosulfan are cytotoxic agents used in the conditioning regime prior to paediatric haematopoietic stem cell transplantation (HSCT). These agents cause suppression of myeloid cells leaving patients severely immunocompromised in the early post‐HSCT period. The main objectives were:...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Solans, Belén P., Chiesa, Robert, Doncheva, Bilyana, Prunty, Helen, Veys, Paul, Trocóniz, Iñaki F., Standing, Joseph F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373705/
https://ncbi.nlm.nih.gov/pubmed/32077123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14260
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