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Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies

Human coronaviruses (hCoV) have become a threat to global health and society, as evident from the SARS outbreak in 2002 caused by SARS-CoV-1 and the most recent COVID-19 pandemic caused by SARS-CoV-2. Despite high sequence similarity between SARS-CoV-1 and −2, each strain has distinctive virulence....

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Davies, Jonathan P., Almasy, Katherine M., McDonald, Eli F., Plate, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373130/
https://ncbi.nlm.nih.gov/pubmed/32699849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.13.201517
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