Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

The ongoing SARS-CoV-2 pandemic has devastated the global economy and claimed nearly one million lives, presenting an urgent global health crisis. To identify host factors required for infection by SARS-CoV-2 and seasonal coronaviruses, we designed a focused high-coverage CRISPR-Cas9 library targeti...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Hoffmann, H.-Heinrich, Schneider, William M., Sánchez-Rivera, Francisco J., Luna, Joseph M., Ashbrook, Alison W., Soto-Feliciano, Yadira M., Leal, Andrew A., Le Pen, Jérémie, Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491511/
https://ncbi.nlm.nih.gov/pubmed/32935098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.11.291716
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