Tuberculosis following PD-1 blockade for cancer immunotherapy

Due to the well-established therapeutic benefit of boosting anti-tumor responses through blockade of the T cell inhibitory receptor PD-1, it has been proposed that PD-1 blockade could be also useful in infectious disease settings, including Mycobacterium tuberculosis (Mtb) infection. However, in pre...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Barber, Daniel L., Sakai, Shunsuke, Kudchadkar, Ragini R., Fling, Steven P., Day, Tracey A., Vergara, Julie A., Ashkin, David, Cheng, Jonathan H., Lundgren, Lisa, Raabe, Vanessa N., Kraft, Colleen S., Nieva, Jorge J., Cheever, Martin A., Nghiem, Paul T., Sharon, Elad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372940/
https://ncbi.nlm.nih.gov/pubmed/30651320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat2702
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