Tuberculosis following PD-1 blockade for cancer immunotherapy

Due to the well-established therapeutic benefit of boosting anti-tumor responses through blockade of the T cell inhibitory receptor PD-1, it has been proposed that PD-1 blockade could be also useful in infectious disease settings, including Mycobacterium tuberculosis (Mtb) infection. However, in pre...

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Publicat a:Sci Transl Med
Autors principals: Barber, Daniel L., Sakai, Shunsuke, Kudchadkar, Ragini R., Fling, Steven P., Day, Tracey A., Vergara, Julie A., Ashkin, David, Cheng, Jonathan H., Lundgren, Lisa, Raabe, Vanessa N., Kraft, Colleen S., Nieva, Jorge J., Cheever, Martin A., Nghiem, Paul T., Sharon, Elad
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372940/
https://ncbi.nlm.nih.gov/pubmed/30651320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat2702
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